Having healed 7 groups through this, with only one disastrous failure (who of course opted to play 'blame the healer'), I've come to realise that not only has ANet created a gloriously epic finale... they've also managed to incorporate PvP elements into it.
Yes, PvP elements in PvE - Oh noes!
While some group setups do make things easier, it is entirely possible to do this event *without* a specific setup. Even without the obligatory minion master. So I'm not going to touch on what does or does not make things easier here in terms of which classes/skills are brought. Any group, playing sanely, can get through this. There've been reports of it being done without a healer - so - not even that archetype is indispensable if you play smart. (Again, very PvP.)
PvP stuff that Battle for Lion's Arch teaches:
1) Don't overextend
Don't run out the front gate into the arms of the waiting army, just because you can.
2) Don't clump up
AoE says hello.
3) Know when to fall back
Watch the battle, not just your target. Watch for if your party members ping energy, call for a fall back, or are in general under so much pressure that *you* decide to call for a fall back.
4) Use the terrain
After Isaiah, it's usually a good idea to retreat to the stairs between the two hills. Because Guild Wars has collision detection, this is perfect 'tanking' country. The main object of mobile affection stands between the two hills. The squishies hide behind the hills, and those that need the higher ground cautiously venture up one hill.
5) Your healer is not God
Play smart. You are responsible for yourself, more than your healer is responsible for you. And even if your healer were God, they wouldn't be able to save you from your own stupidity. Nor are they obligated to.
PvE stuff that you really should do:
Wear an infused armour set. Yes, Blimm's 'weapon' gives an aura. That aura only lasts a set duration, and is gone if you die. That means that if you die just one time, for whatever reason, and don't have infused armour, game over. Oh, and Isaiah brings a Jade Construct - before Blimm's 'weapon' is ready.